Salicylic Acid and Topical Niacinamide acne treatment

Salicylic acid encourages mild peeling of the skin which avoids the blockage of the pores. Keeping the pores open prevents the formation of trapped sebum and dead skin cells. Trapped sebum and dead skin cells are the main source of food for the propionibacterium acnes bacteria. When it comes to germ killing ability, salicylic acid is not as good as benzoyl peroxide but it also does a good job in preventing acne breakouts. Salicylic acid keeps down the population of P. Acnes bacteria by depriving them with their food source instead of directly killing them.

Daily use of salicylic acid causes dryness of the skin and this can be minimized by using Topical Vitamin B5 or Topical Niacinamide. Vitamin B5 is more effective in hydrating the skin compared to Niacinamide. We recommend the use topical niacinamide instead of topical vitamin B5 because topical niacinamide can reduce the skin inflammation caused by acne.


The required concentration for salicylic acid is at least 0.5% according to the FDA monograph (21 CFR 333.310 for OTC acne treatments). Topical niacinamide concentration should be at least 5% in gel form or hydroalcoholic serum. Apply first the 0.5% salicylic acid solution on the face using a cotton ball. Wait for about 30 minutes and then apply the topical niacinamide gel or serum on the face and leave it overnight for maximum effect.


Salicylic Acid Peels in Polyethylene Glycol Vehicle for the Treatment of Comedogenic Acne in Japanese Patients Dermatologic Surgery (OnlineEarly Articles).

Treatment of acne vulgaris with salicylic acid pads.Zander E, Weisman S. Medical Affairs, Sterling Winthrop Consumer Health Group, Sterling Winthrop Inc., New York, New York. “Published Studies on Tissue and Skin Remodeling Copper-Peptides ” by Loren Pickart PhD (April 2003) “Copper and Your Skin: Facelift In A Bottle By William H. Dresher, Ph.D., P.E ( June 2006 ).

Salicylic Acid and Niacinamide for Acne | Salicylic Acid Niacinamide for Acne Treatment | Niacinamide Salicylic Acid

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